At Nautilus, we have a pretty audacious purpose: to positively impact the health and lives of millions around the world by providing ubiquitous access to the proteome. By making it possible for every lab, every researcher, and every clinician to access this groundbreaking frontier of science, we plan to enable important discoveries in biological research and healthcare.
If you’re reading this post, you may already know that the proteome is the full set of proteins in a biological sample and, since proteins drive most biological processes, it is the proteome that determines cellular identity and function in health and in disease. At Nautilus, we’re developing a novel platform that will provide a comprehensive look at the proteome. The platform will enable researchers and physicians to look far beyond the horizons of current technologies and bring the ever-changing proteome into full view. By revealing fluctuations in the proteome that can be linked to cellular function, health, and disease, our platform is designed to enable many new biotech applications across healthcare, agriculture, and more.
On this blog, we share what we believe makes our platform, our leadership, and our team uniquely suited to probe the depths of the proteome. We aim to make the science behind our technologies accessible to the science-curious while giving the science-acquainted the resources they need to learn more. Along the way, we’ll share what motivates us in hopes of inspiring you to become a part of the coming proteomics revolution.
Happy reading!
Proteoform Analysis
A proteoform is any variant of a genetically encoded protein. Each proteoform is defined by its full set of modifications whether those modifications come from alternative splicing, post-translational modification, or any other source. The combinations of alterations found on individual proteins can change properties such as their structures, propensities to bind other proteins, and degradation rates. It’s through the various patterns of modification found on proteoforms that a single gene-encoded protein can adopt many different functions and drive various biological processes. The blog posts in this category cover examples of how proteoforms impact biology. They also explore how the Nautilus Platform is designed for targeted proteoform analysis. Two popular posts from this category include:
Applications of Proteomics
Blog posts in this category cover the many ways scientists are using proteomics, including proteoform studies, to learn more about basic biology, potential biomarkers and drug targets, mechanisms of disease, and more. Two prominent blog series in this category include our “Applications of proteomics in neuroscience” and “Applications of proteomics in cancer” series. Each comes with its own eBook:
Events
Keep up to date with insights from Nautilus’ participation in conferences, webinars, and other events. In these posts, you’ll find curated data and key takeaways from the Nautilus team. Two recent posts from this category include:
Industry Interviews
Find interviews with proteomics experts, biotech entrepreneurs, and Nautilus leaders. These interviews provide insights into developments at Nautilus, proteomics, and biotech more generally. Two popular posts from this series include:
Life at Nautilus
Find interviews with Nautilus team members and discover how their unique backgrounds, skillsets, and motivations make them well suited to work at a groundbreaking next-generation proteomics company like ours. Two popular interviews in this series include:
Nautilus and our Platform
Discover how we’re bringing the proteome into focus with the NautilusTM Proteome Analysis Platform. Here you’ll find posts describing how the platform is designed to conduct broadscale proteomic analyses and targeted proteoform studies. Two popular posts in this category include:
Nautilus in the News
Find announcements about Nautilus, news stories featuring us, and podcasts with team members. Two great posts in this category include:
Proteomics
Learn the basics of proteomics, explore proteomics technologies and techniques, and discover trends in the field. Two popular series in this category include:
Research and Collaborations
Find data and insights from Nautilus projects and collaborations.
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