Discover biological
insights hidden in
your samples
The Nautilus Voyager™ Platform is designed for accessible proteomic analysis that enables you to achieve novel insights through straightforward and reproducible single-molecule quantification of the proteins that matter to your biology of interest.
The Nautilus Voyager™ Platform
The Nautilus Voyager Platform consists of integrated reagents, fluidics, imaging, and ultra-dense nano-array flow cells enabling Iterative Mapping and cloud-based analysis of single-molecule data outputs. It is designed to occupy a typical lab benchtop with standard facility requirements – no bespoke gas or fluidic connections needed.
Current and emerging
applications of Iterative Mapping
Iterative Mapping is a foundational method with endless applications. Explore our current portfolio of applications here. If your desired application is missing, fill out the form below to let us know how you’d like to use Iterative Mapping.
Nautilus Tau Proteoforms Assay
- Quantify up to 768 distinct proteoforms across 6 human brain-derived full-length tau isoforms
- Digital counts of relative abundance normalized to total number of full-length tau counts in counts per million (cpm)
- Median CV <10% (inter-assay)
- Quantify tau proteoforms present at ≥0.1% of total tau
Nautilus Tau Proteoforms Assay
Quantify tau proteoforms at the single-molecule level and unlock deeper insights into neurobiology.
Oncology Proteoforms Assays
Assays quantifying proteoforms derived from the following proteins are currently in development:
- AKT1
- EGFR
- P53
Please fill out the form on the Iterative Mapping Early Access Program webpage to be one of the first to incorporate these assays into your workflows.
Oncology Proteoforms Assays
Quantify proteoforms derived from proteins known to be critical to cancer.
Join the Iterative Mapping
Early Access Program
Interested in using Iterative Mapping
for a different application?
Tell us about it!
Discover what other researchers are
saying about the Nautilus Voyager™ Platform
"Bottom-up proteomics established much of what we know about the proteome by cutting proteins to pieces and reassembling the information. The introduction of Iterative Mapping on the Nautilus Voyager Platform marks the opening of a new era: one where intact, full-length proteins come into the light, and the combinatorial modification landscapes that drive biology are finally within reach."
Don Kirkpatrick, Ph.D.,
Proteomics Scientist and
Biotech Executive
"For decades, we’ve known tau is central to neurodegeneration, but we’ve lacked the tools to fully resolve its molecular complexity. The Nautilus Voyager Platform and advances in single-molecule proteomics are changing that, allowing us to directly observe individual tau molecules and uncover disease-associated signatures that were previously hidden.”
Joel Blanchard, Ph.D.,
Associate Professor, Ichan School of Medicine
at Mount Sinai
"I strongly believe studying proteoforms at scale is the key to understanding biology"
Parag Mallick, Ph.D.
Nautilus Co-Founder and Chief Scientist,
Stanford Professor
"Bottom-up proteomics established much of what we know about the proteome by cutting proteins to pieces and reassembling the information. The introduction of Iterative Mapping on the Nautilus Voyager Platform marks the opening of a new era: one where intact, full-length proteins come into the light, and the combinatorial modification landscapes that drive biology are finally within reach."
Don Kirkpatrick, Ph.D.,
Proteomics Scientist and
Biotech Executive
"For decades, we’ve known tau is central to neurodegeneration, but we’ve lacked the tools to fully resolve its molecular complexity. The Nautilus Voyager Platform and advances in single-molecule proteomics are changing that, allowing us to directly observe individual tau molecules and uncover disease-associated signatures that were previously hidden.”
Joel Blanchard, Ph.D.,
Associate Professor, Ichan School of Medicine
at Mount Sinai
"I strongly believe studying proteoforms at scale is the key to understanding biology"
Parag Mallick, Ph.D.
Nautilus Co-Founder and Chief Scientist,
Stanford Professor